When an unexpected piece of evidence surfaces in the 305, Rosewood and Villa attempt to solve a serious crime involving a very well-off Miami man. Meanwhile, Rosewood struggles to balance a new romantic interest with the demands of his mother, and Villa runs into trouble on the job.
Villa arrests a young man for murder. When Rosie looks at him, he senses he's innocent. He offers to help for free. He first talks to the man and learns he has a chip on his shoulder but he gains his trust. He looks at the crime scene and deduces he couldn't have killed the victim in the manner the police thinks he did. Villa sees a therapist not knowing she's Rosie's girlfriend.
When Rosewood and Villa suspect a brilliant doctor has killed two of his patients, they must find a way to make their case with limited evidence. Meanwhile, Villa spars with Captain Hornstock when he discourages her from pursuing an uncertain case. Also, Rosewood receives an anonymous letter revealing something that could change his life forever.
Rosewood and Villa make it their mission to seek justice for a murder victim who is an ex-con with ties to a Little Haiti gang. Meanwhile, Villa struggles with dreams she's been having, and Rosewood deals with an unexpected turn in his relationship with Kat.
When Captain Hornstock becomes the prime suspect in his third ex-wife's murder, he turns to the only two people he can trust to prove his innocence, Rosewood and Villa, forcing them to repair their severely damaged relationship in hopes of clearing his name. Meanwhile, Shirley's revelations lead to emotional consequences for Rosewood and Pippy.
While testifying for the prosecution during a murder trial, Rosewood engages in a pathology chess match with the expert witness for the defense - his father. Then, when Donna and Beaumont Sr. make an unexpected announcement, it has unforeseen consequences.
Rosewood and Villa are thrust into the underbelly of the everglades when they team up with Hornstock's ex-partner-turned-bounty hunter, Floyd Butters, to catch a murderer. Meanwhile, Pippy is given the opportunity of a lifetime to launch her music career, and Villa tries to reconnect with her mom.
Amidst the glitz and glamour of Miami Fashion Week, there's a plot to kill one of the city's hottest new designers, who turns to Rosewood for help. As the case takes Rosewood and Villa from the catwalk to the perp walk, Rosewood learns of his shared past with the victim. When he enlists the aid of his best friend, Dr. Mike Boyce, Rosewood unintentionally gives Villa the jolt she needs to get back into the dating pool. Potential love also is in the air for Donna, who tries her hand at online dating. Meanwhile, Pippy and TMI find their romance on the skids when Pippy ...
Rosewood and Villa dive into the hip Miami art scene to catch a serial killer who is on the cusp of creating a "masterpiece." When TMI's ex-fiancé, FBI Detective Heath Casablanca, joins the hunting party, he threatens to sabotage Pippy and TMI's relationship. Heath also butts heads with Hornstock, who stands to take over as police chief if he can catch the killer. Meanwhile, an impending lawsuit against Rosewood threatens the lifeline of Magic City Lab and forces Donna to take a long hard look at the way her son lives his life. Also, Rosewood tries to protect Villa ...