Gordon and Bullock search for the source of a new street drug that causes euphoria then death. Meanwhile, Oswald Cobblepot works his way deeper into Maroni's inner circle and Fish Mooney continues to plot against Falcone.
Assassins attack Wayne Manor to try and kill Selina, causing her and Bruce to go on the run. While Harvey and Alfred try to find the kids, Gordon tries to track down the man he believes was behind the attack: Dick Lovecraft.
In an attempt to get his job back, Gordon seeks to capture Jack Gruber, a deranged electronics genius who has escaped from Arkham Asylum. Meanwhile, Falcone struggles to hold onto his empire after Fish Mooney makes her next move.
Fish Mooney reveals a secret of Oswald Cobblepot's, prompting Maroni to take him on a trip to test his loyalty. Meanwhile, Gordon and Bullock hunt down a killer who targets victims with severe phobias and Bruce Wayne confronts Gordon for failing to make progress on his parents' murder case.
Gordon and Bullock set out to stop Gerald Crane, a biology teacher who has been harvesting the glands of his murder victims. Meanwhile, after finding herself in an unusual setting, Mooney continues plotting to gain power, and Falcone attempts to change Maroni's plan for the Penguin. Then, Bruce takes a treacherous hike.
Following several bank robberies, Gordon and Bullock investigate the Red Hood gang. Meanwhile, Selina bonds with Barbara, Penguin faces problems, Fish tries to reclaim her position, and Alfred is visited by an old friend.
While Gordon seeks information about the recent controversy with Commissioner Loeb, Fish's allegiance with the prisoners is questioned when she appears to join forces with Dr. Dulmacher. Meanwhile, after an attack close to home, Bruce deals with the aftermath.
Gordon and Bullock inspect a cold case involving "the Ogre", a serial killer who targets young women in Gotham City. Meanwhile, Fish plots her escape from the Dollmaker, and Bruce and Selina confront Reggie.
Gordon and Bullock continue to investigate the Ogre, who begins to make his move on someone close to Gordon. Meanwhile, Bruce and Selina team up to expose a corrupt Wayne Enterprises employee and Nygma comes to Kristin Kringle's defense.
The Ogre breaks down Barbara's emotions, while Gordon and Bullock track him down. Meanwhile, Penguin leads a massacre, beginning an epic war, while Bruce learns the truth about Wayne Enterprises and Nygma deals with his recent actions.