After an unprecedented global pandemic turns the majority of humankind into violent "Infected," a man gifted with the ability to speak the Infected's new language leads the last survivors on a hunt for Patient Zero and a cure.


Stefan Ruzowitzky


Mike Le (screenplay)





Credited cast:
Natalie Dormer ... Dr. Gina Rose
Stanley Tucci ... The Professor
Matt Smith ... Morgan
Clive Standen ... Knox
John Bradley ... Scooter
Agyness Deyn ... Janet
Frederick Schmidt ... Joe Cocker
Pippa Bennett-Warner ... Linda
James Northcote ... Pete Townshend
Colin McFarlane ... Colonel Pierce
Evie Wray ... Student
Mac McDonald ... Chief of Police
Susanna Herbert ... Anna
Alexandra Doyle ... Refugee
Janis Ahern ... Fox Host


In the pandemic thriller, Patient Zero, humanity is battling intelligent, adrenaline-fueled creatures born from a viral super-strain. After being bitten, human survivor Morgan (Matt Smith) realizes he is asymptomatic and can communicate with the infected, leading the last survivors on a hunt for Patient Zero and a cure. Written by Sony Pictures

Plot Summary | Add Synopsis


Find the Disease. Find the Cure.


Action | Drama | Horror | Sci-Fi

Motion Picture Rating (MPAA)

Rated R for bloody violence, language, and some sexual content | See all certifications »

Parents Guide:

View content advisory »

Did You Know?


Matt Smith plays a character in this movie looking for patient zero. In his first episode on Doctor Who as the doctor he is hunting down prisoner zero. See more »


When the professor is being handcuffed to the chair in the glass cage, his right arm position changes between shots, from resting on the armrest to being tucked behind his back. See more »


The Professor: [as an Infected] Just because I killed my family doesn't mean I didn't love them.
The Professor: [to Morgan] You Are Our Patient Zero
See more »

User Reviews

Not bad, not great, but okay
29 August 2018 | by pontramSee all my reviews

This production has its biggest deficiency in missing directing. It seems that the director here could not contribute much, except a vision of the underground environment. Leading the actors or improving the script wasn't on his agenda, I assume. The plot isnn't really elaborated, the script not very mature, the main actors don't show that much involvement, and production values are not the best. The whole movie is bit of a mess, but surprisingly, it wasn't that bad, Though most things here are cliché, beginning with the charcters, to the relations and most of the dialogs, which sometimes seem to be taken from a Lego construction kit for post-apocalyptic movies, there are some little enhancements, which save the movie from total failing. One enhancement is of course Stanley Tucci's part, who has the easiest work, as the script serves him and him only, where it works against Smith and Dormer for most of their lines - and they both aren't charismatic enough to compensate. But many reviews here criticize the accents, and that is the one point I wouldn't ever do, since it hastn't any real impact on a movie's quality. The premise itself is flawed, as the virus doesn't kill or zombify people, but makes them violent - but not against already infected ones, as it seems (it is said that they roam the surface in packs). So it is a mild Apocalypse, after which we all may live together again but with much roaring and grumbling. Doesn't sound that gruesome for me.

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Release Date:

14 September 2018 (USA) See more »

Also Known As:

Patient Z See more »

Company Credits

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Technical Specs


Aspect Ratio:

2.35 : 1
See full technical specs »

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