After tragedy strikes their only ally within the government, the team is left on their own to stop a surge of animal-related attacks from destroying the city of Geneva, Switzerland. Also, new team member Dariela (Alyssa Diaz) makes a shocking discovery about General Davies (Peter Outerbridge), head of the Noah Objective, and in the Canadian wilderness, Jamie witnesses the animals' broadening effect on the environment and uncovers a troubling detail about Logan.
In an effort to unravel a dark conspiracy within the Noah Objective, the team travels to Vancouver, where it must infiltrate a black-tie event in order to get close to General Davies and stave off an impending animal threat. Also, Jamie and Logan's journey is interrupted when Logan's past comes back to haunt them.
The team travels to Portugal where they square off against a dangerous venom dealer in order to get one step closer to the cure. Also, Jackson's increasingly erratic behavior jeopardizes the entire team.
Jackson faces the most difficult decision of his life. Also, Mitch reluctantly enlists help from his father, Max Morgan (Robin Thomas), to investigate the origin of the final set of triple helix animal bones.
General Davies tries to find Jackson before Mitch and Abraham to prevent the team from making a cure. Jamie, Dariela and Allison try to persuade the Russian government to drop out of the Noah Objective.
Mitch and Jamie find themselves in the middle of an animal attack at the Russian Embassy in Washington, D.C. Meanwhile, Jackson finally gets the answers he's been looking for...and it's from a surprising source.