Santana is the greatest biological weapon developed by the US government. A man that not only can give disease to any person he comes in contact with, but he can take and cure those same diseases. When he is a young boy, the government discovers his unique abilities. They create an accident and steal him from his family. Over the next several years of his life, he is trained as an operative for a secret government agency. After being sent out on a few missions, Santana's conscience takes over. He realizes that the government is involved in unsavory ventures. Santana uses the skills he has acquired to elude his captors. Santana chooses to use his abilities to right the wrongs of everyday people. He is often found roaming the halls of hospitals, healing the undeserving injuries and diseases. He is also found in back alleys giving disease to common criminals, with a catchphrase of "You like to prey on the weak and helpless, it's time for you to feel weak and helpless." General Ramos is in a race to find Santana before the government releases its latest biological weapon for testing. The agents found in Santana's blood hold the cure to this newly developed disease. Rift has other plans for the weapon.