R.J. Palacio got the inspiration to write the book after taking her son out for ice cream, where they saw a child with Treacher Collins Syndrome. Her son cried at the sight of this boy. This story is used in a scene from the film, where Jack Will's (Noah Jupe's) mother is reminding him why it's important to make Auggie feel welcome.
Jacob Tremblay's prosthetic make-up, designed and created by Arjen Tuiten, took an hour and half to apply. It consisted of a skull cap with prosthetic ears attached, a facial prosthetic that covered Jacob's face, and a wig to tie it all together.
The scene where Isabel (Julia Roberts) and Nate (Owen Wilson) are drinking wine towards the end of the movie contains a Pretty Woman homage. Julia Roberts opens a hinged gift box and laughs out loud, just as her character did in Pretty Woman when Richard Gere gives her a necklace.
Isabel's (Julia Roberts') thesis is titled "The Fourth Oder of Vision in the Illuminated Books of William Blake". Many of Blake's illustrations are of people dealing with the grotesque on a deep, emotional level, and many others are related to salvation and spiritually uplifting themes. Both are themes that tie into the character's family life. Blake is best known to movie audiences as the illustrator of the dragon in the Hannibal Lecter film Red Dragon (2002).
For those unfamiliar with the play "Our Town", it has certain similarities to this film as it shares vignettes of various characters at various points in their lives, including both happy times and sad. In the play, Via is in the role of a character who, during the course of the story, changes from a girl to a married woman. She dies when giving birth to her second child, but later returns to the stage to revisit a wonderful day when she was twelve years old. Her goodbye speech takes place shortly before she joins the other characters in the play who had passed away over the years. Sharing certain themes with the film, the town has similarities to the characters and their relationships in this film, including the family dog.
A film installment based on a young adult book franchise has been released in November every year since 2008. The Twilight Saga was released in 2008, 2009, 2011 and 2012. The Hunger Games series was released in 2013, 2014, and 2015, and the Harry Potter/J.K. Rowling's Wizarding World series in 2010, and 2016. Wonder is the first film adaptation based on a children's novel in this slate.