Lost in the Amazon follows Niall McCann's search for missing Royal Geographic Society explorer Col. Percy Fawcett in the Amazon rain forest. Fawcett proposed there was a lost Amazon civilization who left ancient stone city he referred to as "Z" somewhere in the deep rain forest. He was a renowned explorer and cartographer who's previous expedition in 1921 ended in failure. In 1925 he tried again with his son Jack and Jack's best friend Raleigh Rimmell. The 1925 expedition disappeared leaving a tall legend behind. McCann is the latest to attempt to trace and discover what happened to Fawcett, and uses research of Fawcett's notebooks and interviews with natives to get to the bottom of the mystery.