The production had to hire snake wranglers to make sure the areas where they were filming were snake free. Before filming began the wranglers found 25 venomous snakes. The biggest one they found was a 5 foot rattlesnake.
To gain the role of Chuck, actor Blake Cooper continuously campaigned for an audition via twitter. He would send director Wes Ball tweet after tweet after tweet stating that he was made for the role. Wes Ball eventually relented and told Cooper to send his audition to the casting director who stated that Cooper was the perfect Chuck.
Many of the characters' names are taken from historical figures and most are from inventors, mathematicians, philosophers, or scientists to illustrate their intelligence (which was a major plot element in the novel): Thomas (Thomas Edison), Alby (Albert Einstein), Newt (Isaac Newton), Chuck (Charles Darwin), Gally (Galileo), Teresa (Mother Teresa), Winston (Winston Churchill), Ben (Benjamin Franklin) and Frypan, in the novel also called Siggy (Sigmund Freud). Author James Dashner has said that Minho is not named after anyone famous but his niece's Korean husband. The novel also featured other characters such as Aris (Aristotle) and Harriet (Harriet Tubman).
In the book, the walls of the maze were much, much taller which is why the gladers weren't able to climb them to the top. The maze is also contained within a dome. The sky and the weather are all artificial.
Kaya Scodelario's favorite day on set was when she spent an entire shooting day on the top of a tree with O'Brien. She said that was when they really spent time together as actors and got to know each other better.
In the scene where Thomas first writes his name of the wall with the other names there is the name "Alec" which is a reference to the other maze runner series book kill order where Alec is one of the main protagonists
The book features the "Glader's" own slang, including shank, shuck, klunk, greenie, slinthead, shuck-face, and a few others. The movie also has a few here and there. Will Poulter (Gally) and Ki Hong Lee (Minho) revealed their favorites; Will's being shank and Ki Hong's being shuck.
Thomas Brodie-Sangster's favorite scene to film was the scene where he and Thomas (Dylan O'Brien) are sitting by the log and talking about the maze because he said that it wasn't a big scene, it was relaxed
Many of the slang words used by the Gladers first appeared in a sketch on The Ronnie Johns Half Hour (2005), in which a member of the Australian Classification Board gives a lengthy list of acceptable substitutes for the word "dickhead".
At the end of the film, The writer of the book; James Dashner, made a cameo appearance as one of the boards men. It is the scene at the end where Ava Paige is talking, and the camera zooms in on her. The man on her right, is James Dashner.
In the book, Gally is captured by a Griever and taken to WICKED. He is seen after the other gladers arrive at the griever hole and under the control of WICKED he tries to kill Thomas. But instead kills chuck (with a knife) Thomas attacks him and beats him unconscious before the people arrive to rescue them. He plays an important role in the later books
In the book the secret code used to get out of the maze is found from old maze maps from the runners, (FLOAT, CATCH, BLEED, DEATH, STIFF, and PUSH) (Chapter 42) It is discovered by Teresa and told to Thomas not Minho.
In the book when the Gladers get out of the maze and into the WICKED facility everyone is still alive and Gally is with them (having been previously kidnapped). Gally is then remotely commanded by a WICKED scientist to throw a knife, not shoot a gun, at Thomas. Chuck then sacrifices himself for Thomas. The "rescue" team arrives, massacres all of the WICKED scientists, and escorts the Gladers to a "safe hold". In the movie we never see the "safe hold", Gally was never kidnapped (he just miraculously appears at WICKED), and all of the scientists are dead.