When the Friendship Map grows bigger to reflect the world beyond Equestria, the Mane Six realize they'll need a way to spread the message of friendship far and wide. Luckily, Twilight knows just what to do - open a School of Friendship.
When Starlight Glimmer and Sunburst are called by the Cutie Map to visit their old hometown, they discover that their parents are having a problem but, they discover that it wasn't the problem they had to solve.
When the ponies decide to go on a camping trip, Queen Chrysalis creates evil clones of the Mane 6 to help her steal the Elements of Harmony so she can use their power to get revenge on Starlight, only to cause a case of mistaken identity.
When Twilight discovers there's another school of friendship, she and Rarity go to investigate and are shocked to discover that Twilight's idol and Pillar of Old Equestria, Starswirl the Bearded, is enrolled at Friendship U.
When Trixie is invited to bring her magic show to the far-off land of Saddle Arabia, she can think of nopony better to bring along than her great and powerful assistant, Starlight-but, not all friends are meant to travel together.
Fluttershy and Applejack journey to the edge of the map on a Friendship Quest to help a group of creatures called Kirin who are so afraid of hurting each other's feelings, they've taken a vow of silence.