Ryan O'Nan (he also received the Rising Star Award at GIFF) and Michael Weston played off each other excellently as the musical misfits pulled together, by somewhat depressing life events, to road trip to random music venues across America. At one venue, they gain the interest of Cassidy (played wonderfully by Arielle Kebbel), who becomes their road manager. The three of them cram into, what I recall being an old Rabbit, and have those conversations you have while cruising along in tight spaces.
As they pursue their goal of competing at a "battle of the bands" event, they take a discombobulated path from East Coast to West, where their stops at music clubs, frats, and busking pulls in the viewer to the characters' general efforts to succeed and to be accepted. Their music is an integral part of the film, and it guides the story along with the duo's up and downs in their ultimate quest to connect with others.
On a side note, I saw the Brookly Brothers perform after their screening, and their music is just as captivating live as in their film.