According to Doug Ellin, the original cut of the film that was submitted to the MPAA was given the NC-17 rating. Ellin was forced to edit some of the more graphic sexual content, in order to achieve the R-rating.
Domenick Lombordozzi briefly reprises "Dom", Vince's childhood friend who caused him problems in season three, in the montage of people that are watching Drama's embarrassing video on TMZ. He's the one in prison, probably from the police chase he was in, in the episode "reDOMtion".
The front of the Texas mansion, that Ari is seen walking with the movie financiers, and the back patio of the mansion in Santa Barbara, where Ari lands in the helicopter, were both portrayed as the same mansion, where Carlos, the owner of tequila Avion, supposedly lives, in Guadalajara, Mexico, in season seven.
During the movie, Ari Gold is stopped briefly by David Spade, who asks for help. Gold replies that he doesn't know Spade, and runs off. Jeremy Piven who plays Ari Gold, co-starred with Spade in PCU (1994).
Martin Landau made a cameo appearance, playing his character from the series, Bob Ryan. Landau was 86 at the time of the film's release, making him the oldest cast member in the film, followed by Warren Buffet at 84.
During the scene in which Eric is walking down Wilshire Boulevard, along side the LaBrea Tar Pits, Drama and Turtle spot him as they're driving, and begin yelling, "Is that E.? E.! E.!" The large brown building in front of them is the home of E! Entertainment Television's production offices and studios, located at 5750 Wilshire Boulevard.
An actor named Billy Walsh plays an uncredited role as a groomsman. Billy Walsh is the name of the director of "Medellin" from the television series, who also "lovingly" refers to Eric as "suit". He can be seen in the movie with the bowl of molly at the screening party.
During the series - most of the cast uses blackberry. Now you see they are using apple phones - Ari is confused by it he says he doesn't know how to use it in the therapists office - which is a common problem when switching from blackberry to apple
The trivia item below may give away important plot points.
Just before the Golden Globes, when Ari is talking to the gang about his resignation, the guys all get in the Lincoln and the doors shut. Shot from above, it appears to be a direct reference to the television show's opening credits, but in reverse.