[Jenner tells Rick that there is no hope for mankind]
Dr. Edwin Jenner : [Jenner looks to Rick] You do want this. Last night, you said, you knew it was just a matter of time before everybody you loved was dead.
Shane Walsh : What? You really said that? After all your big talk?
Rick Grimes : I had to keep hope alive, didn't I?
Dr. Edwin Jenner : There is no hope. There never was.
Rick Grimes : There's always hope. Maybe it won't be you, maybe not here, but somebody somewhere...
Andrea : What part of 'Everything's gone' do you not understand?
Dr. Edwin Jenner : Listen to your friend. She gets it. This is what takes us down. This is our extinction event.
[in a flashback, Shane leans over Rick's unconscious body at the hospital]
Shane Walsh : Listen to me. If you're gonna wake up, I need you to do it now. Okay? Now. Please, man, just show me a sign. Anything. Please, Rick.
[when a bomb goes off over the hospital building]
[Jenner tells the computer Vi to do an Enhanced Internal View of TS-19's brain]
Shane Walsh : [as the group sees the brain of TS-19] What are those lights?
Dr. Edwin Jenner : It's a person's life... Experiences, memories. It's everything. Somewhere in all that organic wiring, all those ripples of light, is you... The thing that makes you unique. And human.
Daryl Dixon : You don't make sense ever?
Dr. Edwin Jenner : Those are synapses, electric impulses in the brain that carry all the messages. They determine everything a person says does or thinks from the moment of birth to the moment of death.
Rick Grimes : Death? That's what this is, a vigil?
Dr. Edwin Jenner : Yes. Or rather the playback of the vigil.
Andrea : This person died? Who?
Dr. Edwin Jenner : Test subject 19. Someone who was bitten and infected... And volunteered to have us record the process.
[Jenner tells the group what happened to everyone at the C.D.C. facility]
Dr. Edwin Jenner : Well, when things got bad, a lot of people just left. Went off to be with their families. And when things got worse, when the military cordon got overrun, the rest bolted.
Shane Walsh : Every last one?
Dr. Edwin Jenner : No... Many couldn't face walking out the door. They... Opted out. There was a rash of suicides. That was a bad time.
Andrea : You didn't leave. Why?
Dr. Edwin Jenner : I just kept working. Hoping to do some good.
Glenn Rhee : Dude, you are such a buzzkill, man.