The cast and crew shot scenes in New Zealand for two weeks. During shooting, they were treated to a traditional Maori powhiri and karakia by the indigenous peoples of New Zealand. The cast and crew enjoyed shooting in New Zealand and frequently spoke about their love for the country.
In the book Meg and her family are Caucasian, and in the movie the Murry family is multiracial. This became controversial among fans of the book and its sequels, but filmmakers believed a multiracial family would be more relevant and relatable for contemporary audiences. Chris Pine has said that the multiracial family dynamic was actually one of the aspects in the script which attracted him to the project.
There is a diagram of space-time "folding" in the presentation that Mr and Mrs Murray are giving. This shows how two distant points can be brought together without having to travel the distance between them. This fold is where the "wrinkle" in the expression "a wrinkle in time" comes from.
In 2010, it was announced that Walt Disney Pictures retained the film rights to remake the novel, following the television film version aired in 2003. Following the success of Tim Burton's Alice in Wonderland (2010), Disney announced hiring Jeff Stockwell to write the screenplay for Cary Granat and his new Bedrock Studios. Cary Granat had previously worked with Disney on the Chronicles of Narnia and Bridge to Terabithia films. The project's budget was $35 million, which the company compares to District 9 (2009) and Bridge to Terabithia (2007), both of which had less than $30 million. For reasons unknown, the project was put in development hell. It wouldn't be until four years later, on August 5, 2014, that Disney announced that Jennifer Lee would be the screenwriter for the film, who had a new take on the book and would not be working from Stockwell's draft.
Following mixed-to-negative critical reactions and a disappointing box office in the USA, the theatrical release of the film was canceled in several overseas countries such as Belgium and The Netherlands, going straight to VOD instead.
Oprah Winfrey got the role on the spot without Auditioning or getting an offer. She was texting Ava DuVernay one day and she mentioned to her that she's currently developing a new "A Wrinkle in Time Adaption" and she asked if she can work with her and Oprah said "No Problem".
During the Happy Medium's attempt to help Meg focus on her father's location, several different alien landscapes are shown, including one with a herd of furry, tentacled creatures. The Happy Medium exclaims, "Aw, look, it's Aunt Beast!" This is a reference to Madeline L'Engle's original novel, where a kindly, blind alien creature tends to a wounded Meg after an encounter with IT on Camazotz. Meg affectionately nicknames the alien "Aunt Beast."
Chris Pine and Michael Peña have, at least once, already portrayed a character on a planet other than earth. Peña's character was on Mars (briefly) in "The Martian" and Pine has been depicted on numerous planets as Captain Kirk in Star Trek movies. Both also were depicted in space.
The trivia item below may give away important plot points.
Mrs. Who is known for speaking in quotes, and referencing by using the quoted's last name and country. (Although she does sometimes use her own words) This Wrinkle in Time movie has added some popculture references. One of these is near the end, when the Misses say good bye to the children. Mrs Who says " 'Tomorrow they'll be more of us.' Miranda, American." This is indeed a reference to Lin Manuel Miranda's Broadway hit "Hamilton," as a lyric from the song titled "The Story of Tonight."