Stranded at a motel for the night because of the postponed cross country meet, Scott and the others suffer strange experiences that cause them to believe members of their own group may be the mysterious killer's newest targets.
With the threat growing far more personal and time running out on innocent lives, Scott is forced to make a difficult choice in order to save both friends and family while, at the same time, Derek and Peter try to figure out how to save Cora's life.
Stiles is put into a mental hospital where he believes he will be safe from the Nogitsune. Will he be as far away from it as he thinks or closer than ever? Meanwhile Scott, Allison and Lydia look for a cure for Stiles.
With the Nogitsune still in control of their friend, Scott and Lydia find an unlikely ally in Peter Hale. Elsewhere, the effects of the Nogitsune have given Chris, Alison and Kira some trouble with four out-of-control werewolves.