| Episode cast overview, first billed only: | |||
| Jack Coleman | ... | Noah Bennet | |
| Greg Grunberg | ... | Matt Parkman | |
| Robert Knepper | ... | Samuel Sullivan | |
| James Kyson | ... | Ando Masahashi (as James Kyson Lee) | |
| Masi Oka | ... | Hiro Nakamura | |
| Hayden Panettiere | ... | Claire Bennet | |
| Zachary Quinto | ... | Sylar | |
| Sendhil Ramamurthy | ... | Mohinder Suresh | |
| Cristine Rose | ... | Angela Petrelli | |
| Milo Ventimiglia | ... | Peter Petrelli | |
| Kate Vernon | ... | Vanessa Wheeler | |
| Deanne Bray | ... | Emma Coolidge | |
| Dawn Olivieri | ... | Lydia | |
| Todd Stashwick | ... | Eli | |
| Elizabeth Lackey | ... | Janice Parkman (as Lisa Lackey) | |
H.R.G. recruits Matt to help him take down Samuel, as they use his long-lost love, Vanessa, to lure him to them, but Samuel has his own plans for Vanessa in the works. Meanwhile, Hiro and Ando go to extreme lengths to save Dr. Suresh. Elsewhere, Peter's introduction of Emma to his mother brings forth visions of a very grim future. Written by NBC Publicity