The opening credits are placeholders for what was in the script, since Director Tim Miller (who asked Blur Studio's Layout Supervisor Franck Balson to remove his quickly) and Ryan Reynolds were the only ones. "As written by Deadpool"; "Some douchebag's film, Starring God's perfect idiot (referring to Ryan. Accompanied by an Easter Egg of Ryan's People Magazine cover as Sexiest Man Alive.); "A hot chick"; "A British villain"; "The comic relief"; "A moody teen"; "A CGI character"; "A gratuitous cameo"; "Produced by asshats"; "Written by the real heroes here"; "Directed by an overpaid tool". There are Easter Eggs as well: The card in the wallet of Ryan in a green suit, a blurry Killebrew being on the phone, the thug with the lighter was originally a filmed joke in reference to Colin Farrell in Daredevil (2003), "Rob L." on the coffee cup is Rob Liefeld, the little sex key-chain, the Orange Number 5 card, and the Hello Kitty.
The scene after the credits shows Deadpool in a bathrobe, making fun of you, the viewer, for sticking around for so long. It is an homage to the post-credit scene in Ferris Bueller's Day Off (1986). He also talks about the sequel, and says it will feature Cable. Then he makes a few jokes about the casting, and pokes at other movies that usually tease future movies in these scenes. The final "chika-chikaa" he does refers to the song "Oh, Yeah", by Yello, which is featured in that movie.
The opening credits appear in a zoom out of a frozen moment from Deadpool's highway fight. The zoom shot contains a variety of jokes and Easter eggs, and ends with a children's drawing of the title character.