Though they did not appear on screen together, both Mark Pellegrino and Titus Welliver play important roles in the series 'Supernatural'. Mark Pellegrino as Lucifer and Titus Welliver as War, 1 of The 4 Horsemen.
In Lost: Live Together, Die Alone (2006), Sayid wondered why the remaining foot of the large statue only has four toes. Although the question is never explicitly answered in the series, this episode provides a good look of the full statue (we only saw the back of it in Lost: LaFleur (2009)), revealing that it has the body of a human, and the face of an animal (hippopotamus). The implied reason for the statue having four toes on its feet is because it does not depict a human, but a human-animal hybrid (later revealed to be the Egyptian goddess Taweret).