After escaping from Abstergo, Desmond Miles is led to an assassin safe house by Lucy Stillman, and accesses the genetic memories of Ezio Auditore da Firenze, his ancestor from 15th Century Renaissance Italy. After witnessing his father and brothers murdered, Ezio becomes an assassin and vows revenge on those who committed the crime. With the help of family and real historical figures, including Leonardo da Vinci, Ezio uncovers a greater conspiracy which would lead him directly to the religious hub of the world and a Spaniard by the name of Rodrigo Borgia, the man who would become Pope Alexander VI.
The truth is written in blood
Did You Know?
This marks the sixth of seven games that Jesper Kyd has made music for in which the main protagonist is an assassin. The first four being the Hitman series and the last three being the Assassin's Creed series. See more
While at the hideout, Desmond seems to insinuate that he's never had any experience as an assassin. However, in Assassin's Creed, Desmond retorts Dr. Vidic's statement that "he's an assassin", saying that he "doesn't do that, not anymore." Desmond also lived amongst assassins during his early years, it's only safe to assume that Desmond has some experience as an assassin, unless, as the story states, he ran away from the commune too soon to learn anything valuable. See more
Ezio Auditore da Firenze
[about to fight Rodrigo Borgia, hand-to-hand style
It's over Rodrigo. No more tricks, no more ancient artifacts, no more weapons. Let's see what you are made of, old man!