The film is the first studio production to adopt green filmmaking initiatives aimed to reduce CO2 emission. Garbage was reduced by half, thanks to the various bins for recyclable material. Caterers used ceramic and washed dishes as opposed to throwaway products. Vehicles on the set used biodiesel fuel.
Jim Gaffigan who plays Lowell in the film is a stand up comedian who often tells a joke about the fact that the male seahorses give birth, saying that a stubborn scientist incorrectly identified the male so he when questioned he said that the males have the babies. In the film Roderick mentions that he loves seahorses because the males have the babies and wishes he could give birth to LN's babies.
The trivia item below may give away important plot points.
As of 2017, This is the only Sam Mendes film not to have a bittersweet ending where a pivotal character dies at the end. In this film, no-one dies and the ending where Burt and Verona find a home has an entirely happy tone.