Dan is head-hunted by Mike Fuller for a prestigious job in Strasbourg. At the same time his old mentor Professor Paul Burnett, suffering from pancreatic cancer, asks him to operate on him. Louise leaves Alex, and Dan admits to Maddie that he's in love with Louise. Elliott practices tough love on James as he recovers from his shoulder wound and his withdrawal from drugs but to no avail. Jac hears about the consultant position in AEU. Although the CEO, Jayne Grayson, had withdrawn it when Lola told her she wanted the job, now Jac wants it. He later finds out that it was one of Joseph's jokes to wind her up. Dan asks Jayne to let him out of his contract early so that he and Louise can go away together. He tells Alex who tells Dan that he is dead to him and they fight. In the end he goes to Strasbourg on his own when Louise tells him she doesn't know what she wants. Maddie is devastated when he leaves.