The guys are surprised to see a beautiful young woman in Sheldon's office. They are even more surprised when they learn that she is Sheldon's fraternal twin sister, Missy Cooper, who is in town only for two days to attend a friend's wedding. Against Sheldon's wishes, Leonard invites her to stay with them, which she accepts. Leonard, Howard and even Raj (who is participating in a pharmaceutical study, which includes testing a new drug to overcome extreme shyness) fawn over Missy. Using the argument of potential genius offspring, Leonard convinces Sheldon, who abhors physical and emotional contact even with family, that he needs to act brotherly in looking out for Missy's best interests when it comes to finding a suitable boyfriend. Who better in that role than his roommate. Ultimately, the guys come to a solution on who should pursue Missy. But what will Missy have to say about their choice?
Did You Know?
The original title, still used internationally in English-speaking territories, is "The Shiksa Indeterminacy". See more
The people already outside Sheldon's office appear to be observing Sheldon and his sister but don't have the vantage to see them as Howard being so close to door already had a narrow view. See more
If you can eat this cheese without farting, you can sleep with my sister.
In the opening scroll of the time line when it gets to 91,000 there is a mistake the dates read 93,000BC 92,000BC 91,0009C 90,000BC for some reason 91,000 is a 9c not a BC. See more
Features Wii Sports
History of Everything
Written by Barenaked Ladies
Performed by Barenaked Ladies
[Series theme song played during the opening titles] See more