Producer Jason Blum reiterated that, while it would not be the final film in the series, it will be the last Halloween movie under Blumhouse, with the rights of the film series reverting to producer Malek Akkad following the release of Ends. When Akkad himself was asked about the future after Ends, he half-jokingly quoted his late father Moustapha Akkad, who had always quoted series star Donald Pleasence: when asked how many Halloween movies he was going to make, he laughed and said, "I'm going to stop at 22."
In the beginning of the film, the movie that Corey and Jeremy are watching is John Carpenter's The Thing (1982), a clear reference to the original where Laurie and Tommy were watching the original The Thing from Another World (1951) and also a reference to Carpenter who directed both the original Halloween as well as The Thing (1982).
Toward the last act of the film, Allyson can be seen wearing an outfit similar to what Laurie Strode wore during the original Halloween (1978).
Corey Cunningham (Rohan Campbell) is a new character inspired by Arnie Cunningham (Keith Gordon) from Christine (1983). When we are introduced to Corey in Halloween Ends, he is shown to have a similar haircut, an identical blue button-up shirt and a pair of black glasses reminiscent of Arnie's in Christine.
Jamie Lee Curtis mentioned that this movie will be her last time playing Laurie Strode after appearing in Halloween (1978), Halloween II (1981), Halloween H20 (1998), Halloween Resurrection (2002), Halloween (2018), Halloween Kills (2021), and this movie.