Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.

Director:

Vincenzo Natali

Writers:

Vincenzo Natali (screenplay), Antoinette Terry Bryant (screenplay) | 3 more credits »
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Popularity
3,374 ( 45)
4 wins & 23 nominations. See more awards »

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Cast

Complete credited cast:
Adrien Brody ... Clive Nicoli
Sarah Polley ... Elsa Kast
Delphine Chanéac ... Dren (as Delphine Chaneac)
Brandon McGibbon ... Gavin Nicoli
Simona Maicanescu Simona Maicanescu ... Joan Chorot
David Hewlett ... William Barlow
Abigail Chu ... Child Dren
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Storyline

Two young rebellious scientists are told by their employers to halt groundbreaking work that has seen them produce new creatures with medical benefits by splicing together multiple organisms' DNA. They decide to secretly continue their work, but this time splicing in human DNA. Written by Anonymous

Plot Summary | Plot Synopsis

Taglines:

A secret experiment will break the laws of science and create an animal human hybrid. See more »

Genres:

Drama | Horror | Sci-Fi

Motion Picture Rating (MPAA)

Rated R for disturbing elements including strong sexuality, nudity, sci-fi violence and language | See all certifications »

Parents Guide:

View content advisory »
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Did You Know?

Trivia

Baby Dren was created using CGI. However, in the scene where she is lying on the examining table breathing while asleep, a puppet was used. See more »

Goofs

When Dren hangs upside down from the rafter in the barn, her dress doesn't fall down around her shoulders. See more »

Quotes

Elsa Kast: If you could understand crazy, it wouldn't be crazy.
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Crazy Credits

The cast credits and finally the title are scattered throughout the opening credits, instead of appearing consecutively. See more »

Alternate Versions

Finnish and German Blu-rays are 108 min. versions. US and UK versions 104 min. See more »

Connections

References Bonnie and Clyde (1967) See more »

Soundtracks

Zeppelin Interpolation
Written and Performed by Bob Wiseman
Courtesy of The Artist
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User Reviews

 
Playing of God
9 April 2011 | by claudio_carvalhoSee all my reviews

Clive Nicoli (Adrien Brody) and Elsa Kast (Sarah Polley) are scientists of the Newstead Pharmaceutics researching the splice of DNA from different animals to form new genetic beings and find medical benefits to mankind. They have just created the hybrid Ginger and Fred and now they intend to join together human DNA to alter the genetic structure of their experiment. When the senior management calls off their experiment, they decide to secretly proceed and they generate a life form with human characteristics. They call it Dren (Delphine Chaneac) and Elsa is very fond of their creation that grows up fast and showing intelligence. When the company shutdown their experiment, they bring Dren to Elsa's abandoned farm and the scientists raise Dren like a daughter. But when it reaches adulthood, the sex drive of Dren is activated and Clive and Elsa learn that they have a serious problem to resolve.

"Splice" is a dramatic sci-fi horror film with the story of two young unethical scientists that decide to play God. The plot is unoriginal but is attractive and engaging, specially because the trio formed by Sarah Polley, Adrian Brody and Delphine Chanéac. The childhood trauma of Elsa is absolutely out of the context and a diversion to the mainstream. The special effects and make-up are awesome, transforming the gorgeous French actress Delphine Chanéac in a creature with an exotic beauty. My vote is seven.

Title (Brazil): "Splice – A Nova Espécie" ("Splice – The New Specie")


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Details

Country:

Canada | France | USA | Germany

Language:

English | French

Release Date:

4 June 2010 (USA) See more »

Also Known As:

Splice See more »

Filming Locations:

Ontario, Canada See more »

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Box Office

Budget:

$30,000,000 (estimated)

Opening Weekend USA:

$7,385,277, 6 June 2010

Gross USA:

$17,010,170

Cumulative Worldwide Gross:

$27,127,620
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Company Credits

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Technical Specs

Runtime:

Sound Mix:

SDDS | DTS | Dolby Digital

Color:

Color

Aspect Ratio:

1.85 : 1
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