| Cast overview, first billed only: | |||
| Will Ferrell | ... | Megamind (voice) | |
| Brad Pitt | ... | Metro Man (voice) | |
| Tina Fey | ... | Roxanne Ritchie (voice) | |
| Jonah Hill | ... | Tighten (voice) | |
| David Cross | ... | Minion (voice) | |
| Ben Stiller | ... | Bernard (voice) | |
| Justin Theroux | ... | Megamind's Father (voice) | |
|
|
Jessica Schulte | ... | Megamind's Mother (voice) |
| Tom McGrath | ... | Lord Scott / Prison Guard (voice) | |
|
|
Emily Nordwind | ... | Lady Scott (voice) |
| J.K. Simmons | ... | Warden (voice) | |
|
|
Ella Olivia Stiller | ... | Schoolchild (voice) |
|
|
Quinn Dempsey Stiller | ... | Schoolchild (voice) |
|
|
Brian Hopkins | ... | Prisoner (voice) |
|
|
Christopher Knights | ... | Prison Guard (voice) |
After super-villain Megamind (Ferrell) kills his good-guy nemesis, Metro Man (Pitt), he becomes bored since there is no one left to fight. He creates a new foe, Tighten (Hill), who, instead of using his powers for good, sets out to destroy the world, positioning Megamind to save the day for the first time in his life. Written by IMDb Editors
Anti-heroes are damn popular but not this underdog. There haven't been any animated movie which tells you a story about an under-dog villain. This is one.