A book of the same name written by Alex Borstein (voice of Lois Griffin) and staff writer Cherry Chevapravatdumrong was released in conjunction with this episode.
There were two working titles for this episode: Lois Pewterschmidt Griffin, and Commander in Queef.
It's learned that Brian has a Ziggy tattoo.
"It Takes A Village Idiot, And I Married One" is a reference to former First Lady Hillary Clinton's book "It Takes a Village to Raise a Child."
The sequence with the 18th Century wigs and Stewie playing different composers on the keyboard is a reference to the 1984 film, "Amadeus", about Wolfgang Amadeus Mozart.