During the opening scenes it is revealed that the events occur during the Antarctic winter of 1982, yet the landscapes are brightly lit by sunlight. Antarctic winters are dimly lit in perpetual twilight at the coast and for a few weeks even completely dark. The Norwegian base in the film is supposedly located inland (nearer the pole) where it becomes darker than at the coast. Bright sunny days are therefore impossible during winter, and storms are the norm rather than the exception.
The very first time we see Kate, when she is examining the extracted specimen, she is listening to music on molded plastic headphones that were not available in 1982. Smaller headphones such as these, designed at the time for listening to Walkman-like portable equipment would have had a metal band going over the head, holding the earpieces in place.
The dog in the final scene (intercut with closing credits) has inconsistent coloration because two different dogs were cast. The initial escape shots were filmed in 2011 and the subsequent aerial shots were taken from the John Carpenter film The Thing.
When Lars is guarding the helicopter pilots, he yells at them a line in Norwegian which the subtitles mistranslate as, "Don't move, demons". An accurate translation of the line would be, "Take it fucking easy".
When Kate is introduced, she is examining a cave bear. She is doing so under normal room temperature conditions. Hence the corps of the animal will thaw and rapidly decay. Specimen like frozen animals are kept frozen all the time to prevent the decay.
Near the beginning, when flying to the Antarctic base, Dr. Kate Lloyd (Mary Elizabeth Winstead) is shown flying in a helicopter without hearing protection or headphones (one of the characters motions her to put them on so they can converse).
Flying in a cargo helicopter is painfully loud (120db or higher) and there is no way that anybody could fly in one for hours without protecting their hearing. In fact, it's mandatory on the majority of flights.
Dr. Sander Halvorson speaks fluent Danish without an accent to his fellow Norwegians. Actor Ulrich Thomsen is Danish.
Danish and Norwegian people can, for the most part, understand each other. In some cases there might be a confusion, as the Danish language can be hard to follow, but this still doesn't qualify as a goof.
When Kate Loyd is inspecting the mouths of her colleagues for fillings she appears to be using an LED flashlight which did not exist in 1982. It was not an LED flashlight. It does look like the beam from the light is touched up with special effects to make it more apparent, but this is not a goof.
The Thule Air base is not Norwegian. It is located in Greenland and is a U.S. Air Force base. However, it is a fictional base in a fictional movie. Therefore not intended to be the real Norwegian camp in Antarctica.
In the 1982 film, we see a videotape of the Norwegian crew (the crew in this installment) blow up the ice-layer on top of the spaceship with dynamite, yet in this film they don't blow up the ice-layer.
The goof item below may give away important plot points.
towards the end in the space ship scene, Kate is stuck in a corridor corner with the alien desperately trying to reach her in vain with its tentacles. Earlier in the film there were several scenes when the alien was able to remove its limbs to attack its prey so it is illogical why it did not use this method to reach Kate.