This is Laura Innes's final episode as a series regular. Although technically she wasn't a main cast member as long as Noah Wyle was (she would have surpassed him after season 13), her character is the longest-running one over the course of the show (excluding background nurse characters such as Haleh and Malik), having worked at the hospital from 1995 to 2007 (versus 1994 to 2005 for Wyle's character). After her departure, the entire cast from the first five seasons is gone. Goran Visnjic, the oldest remaining cast member at this point, joined at the beginning of the 6th season. Innes returned for guest appearances in 2008 and 2009.
The title comes from the gospel of Mark and was used by Abraham Lincoln describing a country that is half free and half slave. "A house divided against itself cannot stand."
Gracie asks Alex if he knows who said, "Sarcasm is the lowest form of wit...". The answer is: Oscar Wilde The full quote is: " Sarcasm is the lowest form of wit but the highest form of intelligence"
Mekhi Phifer and Keith David both had roles in the 1995 film Clockers.