Leonard Hofstadter and Sheldon Cooper are both brilliant physicists working at Cal Tech in Pasadena, California. They are colleagues, best friends, and roommates, although in all capacities their relationship is always tested primarily by Sheldon's regimented, deeply eccentric, and non-conventional ways. They are also friends with their Cal Tech colleagues mechanical engineer Howard Wolowitz and astrophysicist Rajesh Koothrappali. The foursome spend their time working on their individual work projects, playing video games, watching science-fiction movies, or reading comic books. As they are self-professed nerds, all have little or no luck with women. When Penny, a pretty woman and an aspiring actress from Omaha, moves into the apartment across the hall from Leonard and Sheldon's, Leonard has another aspiration in life, namely to get Penny to be his girlfriend.
When beauty meets the brains.
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Did You Know?
Season 2 ending and Season 3 beginning are 3 months apart, Season 3 ending and Season 4 opening are 4 months apart, Season 4 ending and Season 5 opening are also on the same day, with Season 4 ending with Penny (Kaley Cuoco
) and Raj (Kunal Nayyar
) in bed together while Season 5 begins just a few hours after that. Season 5 ends with Howard (Simon Helberg
) in space while Season 6 starts a week after his launch. Season 6 ends with Leonard (Johnny Galecki
) going to the North Sea expedition while Season 7 starts 4 months after his departure. Season 8 starts 45 days after Sheldon (Jim Parsons
) departs on his soul-searching train trip. See more
In numerous episodes, Sheldon is heard to use the phrase "off of". Example - You get OFF a bus, not OFF OF. This is grammatically incorrect, and as such, would never be used by Sheldon Lee Cooper and his eidetic memory. See more
[after a motorcycle accident, which no one asks him about
My leg is killing me, thanks for asking.
One of the final cards to appear in the credit sequence is the vanity card for Chuck Lorre Productions. In keeping with his practice on "Dharma and Greg" and "Two and a Half Men", there is a different message on the card each week, written by Chuck Lorre himself. See more
History of Everything (Instrumental)
Composed by Barenaked Ladies
Performed by Barenaked Ladies
Played during the end credits See more