Leonard Hofstadter and Sheldon Cooper are both brilliant physicists working at Cal Tech in Pasadena, California. They are colleagues, best friends, and roommates, although in all capacities their relationship is always tested primarily by Sheldon's regimented, deeply eccentric, and non-conventional ways. They are also friends with their Cal Tech colleagues mechanical engineer Howard Wolowitz and astrophysicist Rajesh Koothrappali. The foursome spend their time working on their individual work projects, playing video games, watching science-fiction movies, or reading comic books. As they are self-professed nerds, all have little or no luck with women. When Penny, a pretty woman and an aspiring actress from Omaha, moves into the apartment across the hall from Leonard and Sheldon's, Leonard has another aspiration in life, namely to get Penny to be his girlfriend.
When beauty meets the brains.
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Did You Know?
Howard is the only one you never hear vomiting. Sheldon: S3E15, S6E7, S11E11 Leonard: S2E9, S3E2 Penny: S3E2, S3E15, S5E8 Raj: S4E13 Bernadette: S10E5 Amy: S4E21, S11E11 See more
Whenever anyone is using the stairs in the apartment building, it is obvious that each floor is the same set, slightly redecorated. This can be most easily seen in the distinctive marks on the lamps that are next to each apartment doors (especially the one on the left.) See more
[after a motorcycle accident, which no one asks him about
My leg is killing me, thanks for asking.
One of the final cards to appear in the credit sequence is the vanity card for Chuck Lorre Productions. In keeping with his practice on "Dharma and Greg" and "Two and a Half Men", there is a different message on the card each week, written by Chuck Lorre himself. See more
History of Everything (The Big Bang Theory Theme)
Music & lyrics by Barenaked Ladies
Performed by Barenaked Ladies
Played during the opening titles See more