The sixth part of the spy thriller series took $61.2 million on its opening weekend, setting a new record for the franchise in which Cruise plays secret agent Ethan Hunt.
As of Aug. 1, 'Mission: Impossible - Fallout' had reached $83.9 million in domestic box office and $200 million worldwide.
But it is already in Cruise's top 20 domestic box-office performances of his career, after just a week in theaters.
It has buried 'The Mummy,' which grossed $80.2 million in 2017, and outgunned 'Jack Reacher,' which made $80.1 million in 2012. It has also surpassed older Cruise movies such as 'Cocktail,' which took $78.2 million in 1988, and 'Days of Thunder,' which raced to $82.7 million in 1990.
'Mission: Impossible' movies comprise four of the top five box-office hits for Cruise. But the movie star's No. 1 title at the domestic box office remains 'War of the Worlds,' which holds the top slot with $234.3 million in 2005.
'Mission: Impossible - Fallout' also still has a way to go before it passes series-record-holders 'Mission: Impossible II,' which took $215.4 million domestically in 2000, and 'Mission: Impossible - Ghost Protocol,' which set the series' worldwide record with $694.7 million at the box office in 2011.
The coming weeks will reveal if Cruise's latest 'Mission' will see it join its previous instalments near the top of the chart.
See the full list of Tom Cruise's movies at the box office here.