Homer Simpson in: 'Kidney Trouble'

Homer mentions not wanting to miss Inside the Actors Studio (1994). The "Simpsons" cast themselves appeared on the show as guests in 2003; after brief recaps of their histories in show business and how they came together, they entertained host James Lipton and the audience by answering questions in character (Julie Kavner insisted on having stills of Marge on screen while doing Marge's voice, as she didn't want the television audience to view her facial expressions while she was in character).

There are numerous errors in regard to the premise of Grampa's kidneys exploding due to holding in urine too long. 1) Urine is stored in the bladder, not kidneys (kidneys process liquid into urine), so if anything his bladder should have exploded. 2) His bladder or kidneys would not have exploded from holding in urine; all that would have happened would have been that he would just have involuntarily urinated in the car. 3) If Grampa's kidneys did explode, he would die almost immediately from sepsis and internal bleeding, not live long enough to go to the doctor and get X-rays.

Featured in The Simpsons: Behind the Laughter (2000)