It's 1956 and Jack Cleary is a top-notch detective on the Los Angeles police force. Framed by mobsters for taking bribes, he's drummed out of the force where he hits the bottle and the skids. Jack's brother owns Nick Cleary Detective Agency, and after he's murdered while working a case, Jack takes over his brother's Agency. While trying to find his brother's killer, Jack gets his self-respect back. Along with his brother's agency, he inherits his brother's nutty secretary and a former delinquent sidekick named Johnny Betts.