| Episode cast overview, first billed only: | |||
| Kirk Acevedo | ... | Miguel Alvarez | |
| Ernie Hudson | ... | Warden Leo Glynn (credit only) | |
| Terry Kinney | ... | Tim McManus | |
| Rita Moreno | ... | Sister Peter Marie Reimondo | |
| Harold Perrineau | ... | Augustus Hill | |
| J.K. Simmons | ... | Vern Schillinger | |
| Lee Tergesen | ... | Tobias Beecher | |
| Dean Winters | ... | Ryan O'Reily | |
| Mason Adams | ... | Mr. Hoyt | |
| Betty Buckley | ... | Suzanne Fitzgerald | |
| Robert John Burke | ... | Special Agent Pierce Taylor | |
| Bobby Cannavale | ... | Alonzo Torquemada | |
| Reg E. Cathey | ... | Martin Querns | |
| Anthony Chisholm | ... | Burr Redding | |
| Kevin Conway | ... | Seamus O'Reilly | |
In the series finale, Oz is in upheaval after the return of Martin Querns. Meanwhile, Howell and Robson each receive troubling news and the O'Reilys try to make amends. Finally, the prison production of 'Macbeth' ends with a staggering final act. Written by Anonymous