The comedy segment is Sweeps Ahoy!, featuring a reunion of Wagon Train, mini streakers, Joel being the victim of a mysterious crime, La Bamba being replaced with a sexy model, Conan starting a rumor that Max is dead, debuting a new character named Sam who's Jessica Simpson's stupid brother, and showcasing a made-for-TV movie called "Shafted". The second comedy segment has Conan visiting Cloppy the horse. Patrick Stewart is interviewed about his role in the Broadway play The Caretaker; Regina Hall is interviewed about her new movie Scary Movie 3; The Strokes perform.
—Ian Lueck