"It's not easy being green", the phrase which this episode's title derives from, is actually a song written by Joe Raposo and was originally performed by Kermit the Frog for Sesame Street (1969). The phrase appears in pop culture as an expression of melancholy.
This episode marks the first appearance of Dr. Alice Upton, Pathologist.
Eriq La Salle (Peter Benton), Megan Gallagher (Kathy Snyder), Yvette Freeman (Nurse Haleh Adams), William H. Macy (Dr. David Morgenstern), Megan Cole (Dr. Upton), Michael Bryan French (Dr. MacGruder) and Richard Minchenberg (Dr. P.K. Simon) have all appeared on L.A. Law.
Michael Bryan French (Dr. MacGruder), Lisa Waltz (Mrs. Wimbur), Jennifer Rhodes (Mrs. Henry), Michael Alldredge (Ray's Dad) and Josette DiCarlo (Mrs. D'Angelo) have all appeared on Quantum Leap.