There are family businesses and then there are family businesses.
In Sam and Dean's case, their family business consists of "saving people and hunting things."
And as we've seen over the course of 14 seasons, some of these "things" are pretty darn nasty.
Related: Supernatural Season 14 Episode 16 Review: Don't Go Into the Woods
From demons to nightmarish creatures full of teeth to even Death himself, here are 21 of Sam and Dean's most frightening foes.
We've excluded some of the more popular and well-known ones like Lucifer, Eve, Azazel and others because every monster (or demon) deserves their due.
Related: Supernatural to End After Season 15
Which of Sam and Dean's foes do you think was the most frightening? Which ones should have been on this list?
Click through the list below and let us know in the comments!
Relive all of Sam and Dean's nightmares when you watch Supernatural
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