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Snakes on a Plane (2006) Poster

Trivia

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Contrary to popular belief, Samuel L. Jackson's agent insisted that the title be changed, because Jackson "couldn't" work on a film with such a title. When Jackson heard about all of this, he responded with the much cited comment, "We're totally changing that back. That's the only reason I took the job. I read the title."
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(At around forty-four minutes) When the male flight attendant puts the snake in the microwave, he can be seen hitting the "snake" preset button on that microwave, a somewhat unusual preset for a microwave.
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(At around one hour twenty-six minutes) The movie's line "I have had it with these motherfucking snakes on this motherfucking plane!" was voted as the #55 of "The 100 Greatest Movie Lines" by Premiere in 2007.
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Four hundred fifty snakes were used, including one twenty-two-foot-long Burmese Python.
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In March 2006, New Line Cinema, due to massive fan interest on the Internet, allowed for a five day re-shoot to film new scenes to take the movie from PG-13 to an R-rated film (originally the film wrapped principal photography in September 2005). Among these additions is the Samuel L. Jackson character's line, "I've had it with these motherfucking snakes on this motherfucking plane", a line that originated in an anticipatory Internet parody of the movie.
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Most snakes were digitally created, because the real snakes did not move as much as the filmmakers wanted.
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This film's title originated at an after-work happy hour among Hollywood colleagues to see who could come up with the most awful pitch for a movie. Producer Craig Berenson, who worked for DreamWorks at the time, gave his pitch for this movie based on a script called "Venom".
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(At around one hour and twenty-six minutes) The phrase "snakes in the cockpit", which is said in the film, is used by pilots in reference to the high number of complex tasks they have to accomplish.
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A live diamondback rattlesnake was found in a Phoenix, Arizona AMC theater during an August 2006 screening. Another rattler was found nearby in the parking lot.
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Snakes are often mistakenly referred to as "poisonous". However the correct term is "venomous". Poison is ingested whereas venom is injected.
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(At around one hour and eleven minutes) When Sean mentions how hot it is, Agent Flynn responds with "I'm from Tennessee, I hadn't noticed". Samuel L. Jackson is from Tennessee.
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South Pacific Air Lines no longer exists, but was re-created in a fictional sense for the film. The airline began service from Honolulu to Tahiti on April 2, 1960, and folded sometime thereafter.
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The fake working title, that was written on the clappers, was "Anaconda 4".
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The poster design of snakes wrapped around a plane is a reference to the caduceus, which is the symbol for medicine.
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The filmmakers named the large Burmese python "Kitty".
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Shia LaBeouf was offered a role but turned it down.
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The character played by Julianna Margulies is on her last flight as a flight attendant, and is leaving to become a lawyer. Julianna Margulies portrayed a lawyer on The Good Wife (2009).
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In television airings of the movie, the often quoted line is changed to "I have had it with these monkey-fighting snakes on this Monday-to-Friday plane!" Ironically, Samuel L. Jackson later ended up fighting monkey type creatures in The Legend of Tarzan (2016) and Kong: Skull Island (2017).
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One of two films starring Samuel L. Jackson released in 2006 that had the word "snake" in the title, the other being Black Snake Moan (2006).
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Ronny Yu was attached to direct, speaking enthusiastically about the project, but bowed out following budget disputes and "creative differences". He was replaced by David R. Ellis.
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In Aqua Teen Hunger Force (2000), season two, episode one, "Super Birthday Snake", Meatwad names his snake "Nathan (Scott) Phillips". One of the lead actors in this snake-themed movie is Nathan Phillips.
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The initial script for the film was one hundred twenty-two pages long, when David R. Ellis signed on to direct. After re-working the script, along with his Producing Director and Samuel L. Jackson, for more than four months, the script was narrowed down to one hundred three pages.
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In 2013, an incident happened with EasyJet Airlines in the U.K., where a man had a snake on-board which panicked all of the passengers on the flight. However, the man later confirmed the snake was not venomous and it was safely removed from the flight.
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Darius Jackson was a stand in for Samuel L. Jackson.
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Spoilers 

The trivia item below may give away important plot points.

Body count: thirty-one. (Plus twenty-nine snakes, one dog, and one cat.)
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