This documentary examines the world AIDS crisis. The camera travels to Africa, where infections overwhelm the public health system and orphans face their own deaths, central Europe, where drug users spread the disease via shared needles, India, where husbands infect wives, and to the U.S., where grass-roots efforts in places like Kansas City confront cultural stereotypes. Interviews include patients, doctors, nurses, the Dalai Lama, and Kofi Annan. The film's tone is compassionate and urgent, the statistics overwhelming. The message: the AIDS epidemic, history's worst, continues.