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The MPAA would not allow the name "Fockers" to be on posters, or part of the main title for the movie, unless the filmmakers could prove that somewhere in America that there was someone with the real last name of "Focker". Apparently, they found somebody, because the movie was granted the name "Meet the Fockers" by the MPAA.
This was the highest grossing film in which Robert De Niro has ever appeared, until Joker (2019) passed it in 2019.
Alanna Ubach, who played Greg's former housekeeper Isabelle, is actually ten years younger than Ben Stiller.
James Brolin was originally approached for the role of Bernie, but turned it down. When director Jay Roach went to approach Dustin Hoffman for the role, Hoffman was talking non-stop, and even out of the point, which made him the instant choice for Bernie.
Barbra Streisand found making the film to be a refreshing experience as it was her first time as just a jobbing actress in twenty-three years. Normally, she's involved in her films more heavily, either as a producer, writer, or director.