| Cast overview, first billed only: | |||
| Ving Rhames | ... | Holiday Heart | |
| Alfre Woodard | ... | Wanda Dean | |
| Jesika Reynolds | ... | Niki Dean (as Jessika Quynn Reynolds) | |
| Mykelti Williamson | ... | Silas | |
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Johnathan Wesley Wallace | ... | Jambalaya Blue (as Johnathan Wallace) |
| Philip Maurice Hayes | ... | Sergeant | |
| Blu Mankuma | ... | Pastor Henry | |
| Lorena Gale | ... | Mrs. Owens | |
| James Kidnie | ... | Penthouse M.C. | |
| Benz Antoine | ... | Fisher | |
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Guy Fauchon | ... | Travel Agent Dan |
| Ron Selmour | ... | LT (as Ronald Selmour) | |
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Patricia Idlette | ... | Mrs. Walker |
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Mary Antonini | ... | Sarah |
| Emy Aneke | ... | Ricky | |
A drag queen takes in a drug addict and her daughter and helps raise the daughter.
I've seen lots of movies with Ms Woodard and not knowingly have seen Mr Rhames in his other movies. Pulp Fiction was way too intense for me and Holiday Heart was something that I decided to watch, but these two actors in this movie are AWESOME!!! Ms Woodard is so convincing as a full-blown, out-there-on-that-end drug user, then to see her as a ghost who needs to finish business on earth in Heart and Soul.......this woman is amazing! And Mr Rhames had me thinking he was indeed a drag queen outside of the movies! Dang, he's good!! One of the best scenes is in the drug store for Nikki and that's all I'm saying!! (Unfortunately, there are women who fit Ms Woodard's striking profile of the drug user and though some do end up as Wanda, many do make it through and become clean and go forward. I hope this was so for the lady who had to live the nightmare with her mother. (If this paragraph has to be removed because it's personal, I understand.))