In the version that airs on the ABC Family channel, the scene near the end in which Greg gets into an argument with the airline stewardess and his subsequent interrogation by an airline official removes all references to the fact that Greg mentioned the word "bomb" on the airplane.
Universal Studios released a Family Friendly version on DVD that re-dubs some of the profanity (the word 'shit' is re-dubbed to 'shoot' and cuts out some content.
DVD version contains deleted scenes including an extended chase after the cat that goes into the crawlspace under the house in which Greg hears different members of the family talking about him. Also included is a scene in which itineraries for the wedding rehearsal are handed out but there are spelling mistakes such as eating at the 'surf-n-turd'. These mistakes are blamed on Greg. This also explains why Jack later yells out for everyone to get their revised itineraries.
The airline version contains some slight modifications to the scene where Greg is on the airplane to leave for home towards the end of the film. In particular, the shot where Greg pushes the flight attendant away as she tries to take his bag is cut.