Release CalendarTop 250 MoviesMost Popular MoviesBrowse Movies by GenreTop Box OfficeShowtimes & TicketsMovie NewsIndia Movie Spotlight
    What's on TV & StreamingTop 250 TV ShowsMost Popular TV ShowsBrowse TV Shows by GenreTV News
    What to WatchLatest TrailersIMDb OriginalsIMDb PicksIMDb SpotlightIMDb Podcasts
    OscarsCannes Film FestivalStar WarsAsian Pacific American Heritage MonthSummer Watch GuideSTARmeter AwardsAwards CentralFestival CentralAll Events
    Born TodayMost Popular CelebsCelebrity News
    Help CenterContributor ZonePolls
For Industry Professionals
  • Language
  • Fully supported
  • English (United States)
    Partially supported
  • Français (Canada)
  • Français (France)
  • Deutsch (Deutschland)
  • हिंदी (भारत)
  • Italiano (Italia)
  • Português (Brasil)
  • Español (España)
  • Español (México)
Watchlist
Sign In
  • Fully supported
  • English (United States)
    Partially supported
  • Français (Canada)
  • Français (France)
  • Deutsch (Deutschland)
  • हिंदी (भारत)
  • Italiano (Italia)
  • Português (Brasil)
  • Español (España)
  • Español (México)
Use app
  • Cast & crew
  • User reviews
  • Trivia
  • FAQ
IMDbPro

Osmosis Jones

  • 2001
  • PG
  • 1h 35m
IMDb RATING
6.3/10
40K
YOUR RATING
Osmosis Jones (2001)
Home Video Trailer from Warner Home Video
Play trailer1:10
1 Video
99+ Photos
Buddy CopDark ComedyHand-Drawn AnimationHigh-Concept ComedyPolice ProceduralSlapstickActionAdventureAnimationComedy

A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.

  • Directors
    • Bobby Farrelly
    • Peter Farrelly
  • Writer
    • Marc Hyman
  • Stars
    • Laurence Fishburne
    • Chris Rock
    • David Hyde Pierce
  • See production info at IMDbPro
  • IMDb RATING
    6.3/10
    40K
    YOUR RATING
    • Directors
      • Bobby Farrelly
      • Peter Farrelly
    • Writer
      • Marc Hyman
    • Stars
      • Laurence Fishburne
      • Chris Rock
      • David Hyde Pierce
    • 181User reviews
    • 69Critic reviews
    • 57Metascore
  • See production info at IMDbPro
    • Awards
      • 1 win & 8 nominations total

    Videos1

    Osmosis Jones
    Trailer 1:10
    Osmosis Jones

    Photos265

    View Poster
    View Poster
    View Poster
    View Poster
    + 261
    View Poster

    Top cast99+

    Edit
    Laurence Fishburne
    Laurence Fishburne
    • Thrax
    • (voice)
    Chris Rock
    Chris Rock
    • Osmosis Jones
    • (voice)
    David Hyde Pierce
    David Hyde Pierce
    • Drix
    • (voice)
    Brandy Norwood
    Brandy Norwood
    • Leah
    • (voice)
    William Shatner
    William Shatner
    • Mayor Phlegmming
    • (voice)
    Ron Howard
    Ron Howard
    • Tom Colonic
    • (voice)
    Kid Rock
    Kid Rock
    • Kidney Rock
    • (voice)
    Kenny Olson
    • Kidney Rock
    • (voice)
    Jason Krause
    • Kidney Rock
    • (voice)
    Joe C.
    Joe C.
    • Kidney Rock
    • (voice)
    Stefanie Eulinberg
    • Kidney Rock
    • (voice)
    Jimmie Bones
    • Kidney Rock
    • (voice)
    Uncle Kracker
    Uncle Kracker
    • Kidney Rock
    • (voice)
    Jonathan Adams
    Jonathan Adams
    • Additional Character Voice
    • (voice)
    Carlos Alazraqui
    Carlos Alazraqui
    • Additional Character Voice
    • (voice)
    Keith Anthony
    • Additional Character Voice
    • (voice)
    Eddie Barth
    Eddie Barth
    • Additional Character Voice
    • (voice)
    Sally Brooks
    Sally Brooks
    • Additional Character Voice
    • (voice)
    • (as Sally Ann Brooks)
    • Directors
      • Bobby Farrelly
      • Peter Farrelly
    • Writer
      • Marc Hyman
    • All cast & crew
    • Production, box office & more at IMDbPro

    User reviews181

    6.340.2K
    1
    2
    3
    4
    5
    6
    7
    8
    9
    10

    Featured reviews

    8jarossi

    Very fun and imaginative

    I thought this movie was very good. The people leaving bad reviews are being too critical. This movie was meant to be fun. The way the inside of the body is a city, the white blood cells are the police, fireman, etc., the lymph nodes were the police stations, veins were highways, the stomach was a bus station/airport type place, and the germs and bacteria were, of course, the criminals, and so on. This movie gives a very imaginative way the body works to fight infection, as if the body was a city of people just like in the real world. You may need to have some sort of knowledge about the body to get some of the puns and jokes, maybe not very young kids will get it, but they will like the animation...this movie is even good for adults. I give the movie 8/10...I thought it was a very entertaining movie!!!!!
    6SnoopyStyle

    animation good, but live action gross and boring

    The Farrelly brothers are dipping into the animation pool. It's colorful and primitive animation. It's pretty good, but that's not really the problem. Surprisingly the problem is Bill Murray and live action stuff.

    Frank Detomello is a slob. He eats a hard boiled egg covered with a deadly germ. And we travel inside Frank to see white blood cell policeman Osmosis Jones (Chris Rock) battle evil virus Thrax (Laurence Fishburne) with the help of Drix (David Hyde Pierce).

    Bill Murray looks awful as he gets sicker and sicker. I have to ask if we're supposed to laugh at Bill? It's just gross. Not the gross out humor that the Farrellys are known for. It isn't funny at all.

    The animated sections are much better. In fact I prefer they cut out the live action stuff. Chris Rock does a good voice. He has good chemistry with David Hyde Pierce's Drix. They need a few more jokes, but I like the City of Frank.
    6Animany94

    A mixed bag.

    I had never heard of Osmosis Jones before, but I grew up watching the animated series based on this movie so I went into it with excitement and a nostalgic drive.

    What I got was rather mixed. Let me explain.

    The live-action parts pretty much sucked in my opinion. This guy named Frank (Bill Murray) is a single father taking care of his daughter and is a really unlikable father figure. How are we supposed to sympathise with a lazy and egotistical doof? I never felt sorry for him one minute. Mix that with gross-out humour which wasn't even helped the slightest by Bill Murray who is usually really funny.

    Enough said about that, because the animated segments were actually pretty awesome. The world inside Frank's was impressive by how it was crafted. How it functions by having a whole community run by a mayor (William Shatner) and a police force of white blood cells and a lot of real-life city stuff showcased a lot of creative effort was put into it.

    It centers on a white blood cells Osmosis Jones (Chris Rock) who is that kind of cop who does things his own way and the others at the police station do not approve of his ways, but he is later assigned to a new case with a partner to keep him on track, a cold pill named Drix (David Hyde Pierce). Sure, it follows all the buddy cop movie clichés with nothing new added, but the world they must explore and the colorful characters they meet make it entertaining albeit predictable.

    Speaking of the colorful cast of characters, the most interesting and memorable of them all has to be the villian Thrax (Laurence Fishburne) who is menacing and merciless and has a deathcount very high for a PG rated movie.

    Without being boring I found that Chris Rock and David Hyde Pierce seemed to do their usual schtick with Rock being hip and a loudmouth and Hyde Pierce doing his quirky and excentric british gentleman voice. But Fishburne surprised me. He could as easily just have put on his Morpheus voice, but he didn't. I'll give him more credit for that.

    The live-action segments is the movie's biggest drawbacks with an unlikable main character and lowbrow humour as you would expect from the farelly brothers, and frankly (no pun intented) the animated segments aren't perfect and the transitions between the two don't always work.

    But overall Osmosis I found Osmosis Jones enjoyable, but flawed. I understand why it failed in theaters, but I have seen so much worse elsewhere.
    thumps80631

    God help me, I really liked this film.

    As an aesthete, this movie goes against everything I stand for, but I found it nonetheless very entertaining. It was like a peculiar yet satisfying mix between the Incredible Journey, Toy Story, and Lethal Weapon or Rush Hour (the whole loose-cannon, loner cop with a new partner bit).

    I found the idea rather original: the human body is like a body of government, the cop is a white blood cell, the "president" was the cell whose will was that of the man (Bill Murray), the villain is a virus who hangs out in seedy areas of the body with shady characters, the bladder is a sort of train station/airport... clever stuff.

    I did have issues with the "What a zit- I mean, what is it?" part, though: it landed on her lip! Wrong! I could have gone the rest of my life without seeing that. Molly Shannon is quite a sport. 7/10
    7bazmitch23

    Good film but has it's flaws

    When you mention the title of this film to someone, they just look at you and say "What?".

    Yeah, nobody went to see this film when it came out. I think it's because how do you market a film like this? Since this takes place in the human body, there's all kinds of gross out humour in it. Some of it is too much for a PG rated film.

    That's my biggest problem with this film and why it wasn't marketed very well. It's gross. The scene where the nose dam breaks and a giant tidal wave of snot comes out is not what you're mean to see in a family film. Especially on the big screen. The scene where Frank vomits on the teacher and it is shown in a newspaper headline, we actually see the vomit. You don't show people vomiting in a PG film. Not only that, but it's part of the story. Making gross out gags part of the story is not a good idea.

    Also, the scene where the zit is ready to pop, we get a big giant close up on it which is enough to make anyone cringe.

    It's almost like Panty and Stocking with Garterbelt. A show loaded with gross out humour. But that was for adults. This is meant to be a family film.

    Now, the stuff I do like about it; the animation is great, it's very creative, (making the stomach the airport, the brain is city hall, the armpits are the steam room, I could go on)Laurence Fishburne was fantastic as Thrax. I kept forgetting it was him. Even if you don't like this film, you have to admit, Thrax is awesome. The music's great too. I like all the body puns as well.

    Not a film for everyone, but has gained a cult following on DVD.

    More like this

    Ozzy & Drix
    6.9
    Ozzy & Drix
    Jimmy Neutron: Boy Genius
    6.1
    Jimmy Neutron: Boy Genius
    The Rugrats Movie
    5.9
    The Rugrats Movie
    Looney Tunes: Back in Action
    5.8
    Looney Tunes: Back in Action
    Cats & Dogs
    5.2
    Cats & Dogs
    All Dogs Go to Heaven
    6.8
    All Dogs Go to Heaven
    Titan A.E.
    6.6
    Titan A.E.
    Hoodwinked!
    6.5
    Hoodwinked!
    Chicken Little
    5.7
    Chicken Little
    The Land Before Time
    7.4
    The Land Before Time
    Space Jam
    6.5
    Space Jam
    Rugrats in Paris
    6.2
    Rugrats in Paris

    Storyline

    Edit

    Did you know

    Edit
    • Trivia
      Bill Murray's character mentions a "National Chicken Wing Festival" in Buffalo, New York. While the festival did not exist during the filming of the movie, this mention caused organizers to create an annual festival in Buffalo. The festival has been held annually on Labor Day weekend since 2002.
    • Goofs
      Chill was sent into Frank as a flu vaccine. While he could have been a live, weakened virus had he been administered via LAIV (FluMist), this variety of the vaccine was not introduced until 2 years after the film was released. So Chill would have had to come from an injection, meaning he would be a dead virus.
    • Quotes

      Thrax: Ebola? Let me tell you something about Ebola, baby. Ebola is a case of DANDRUFF compared to me!

    • Crazy credits
      The title appears as bubbles, which then pop after 5 seconds.
    • Alternate versions
      On some streaming services, the score plays on the soundtrack as opposed to a pop song during the opening scene.
    • Connections
      Edited into Ozzy & Drix: Home with Hector (2002)
    • Soundtracks
      Turn It Out
      Written by Kelvin Mercer, Trugoy the Dove (as David Jolicoeur) and Richard Morninglane

      Produced by R. Thentic and De La Soul

      Performed by De La Soul featuring Yummy Bingham (as Elizabeth "Yummy" Bingham)

      De La Soul appears courtesy of Tommy Boy Music

    Top picks

    Sign in to rate and Watchlist for personalized recommendations
    Sign in

    FAQ19

    • How long is Osmosis Jones?Powered by Alexa

    Details

    Edit
    • Release date
      • August 10, 2001 (United States)
    • Countries of origin
      • United States
      • Denmark
    • Official site
      • Warner Bros. (United States)
    • Language
      • English
    • Also known as
      • Осмозіс Джонс
    • Filming locations
      • Nathaniel Morton Elementary School - 6 Lincoln Street, Plymouth, Massachusetts, USA(school scenes)
    • Production companies
      • Warner Bros.
      • Conundrum Entertainment
      • Warner Bros. Animation
    • See more company credits at IMDbPro

    Box office

    Edit
    • Budget
      • $70,000,000 (estimated)
    • Gross US & Canada
      • $13,596,911
    • Opening weekend US & Canada
      • $5,271,248
      • Aug 12, 2001
    • Gross worldwide
      • $14,026,418
    See detailed box office info on IMDbPro

    Tech specs

    Edit
    • Runtime
      1 hour 35 minutes
    • Color
      • Color
    • Sound mix
      • DTS
      • Dolby Digital
    • Aspect ratio
      • 2.39 : 1

    Related news

    Contribute to this page

    Suggest an edit or add missing content
    Osmosis Jones (2001)
    Top Gap
    What is the Hindi language plot outline for Osmosis Jones (2001)?
    Answer
    • See more gaps
    • Learn more about contributing
    Edit page

    More to explore

    Recently viewed

    Please enable browser cookies to use this feature. Learn more.
    Get the IMDb app
    Sign in for more accessSign in for more access
    Follow IMDb on social
    Get the IMDb app
    For Android and iOS
    Get the IMDb app
    • Help
    • Site Index
    • IMDbPro
    • Box Office Mojo
    • License IMDb Data
    • Press Room
    • Advertising
    • Jobs
    • Conditions of Use
    • Privacy Policy
    • Your Ads Privacy Choices
    IMDb, an Amazon company

    © 1990-2025 by IMDb.com, Inc.