6.3/10
31,994
155 user 79 critic

Osmosis Jones (2001)

Trailer
1:10 | Trailer
A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.

Writer:

Marc Hyman
1 win & 8 nominations. See more awards »

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Cast

Cast overview, first billed only:
Chris Rock ... Osmosis Jones (voice)
Laurence Fishburne ... Thrax (voice)
David Hyde Pierce ... Drix (voice)
Brandy Norwood ... Leah (voice)
William Shatner ... Mayor Phlegmming (voice)
Ron Howard ... Tom Colonic (voice)
Kid Rock ... Kidney Rock (voice)
Kenny Olson Kenny Olson ... Kidney Rock (voice)
Jason Krause Jason Krause ... Kidney Rock (voice)
Joe C. ... Kidney Rock (voice)
Stefanie Eulinberg Stefanie Eulinberg ... Kidney Rock (voice)
Jimmie Bones Jimmie Bones ... Kidney Rock (voice)
Uncle Kracker ... Kidney Rock (voice)
Jonathan Adams ... Additional Character Voice (voice)
Carlos Alazraqui ... Additional Character Voice (voice)
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Storyline

Frank Detorre is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ... Written by Anthony Pereyra <hypersonic91@yahoo.com>

Plot Summary | Plot Synopsis

Taglines:

She's got a jones for Osmosis. Leah. One hot hormone. See more »


Motion Picture Rating (MPAA)

Rated PG for bodily humor | See all certifications »

Parents Guide:

View content advisory »
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Did You Know?

Trivia

William Shatner's first time voice acting in a theatrically released animated film. Later he'd go onto voice Kazar the Wildebeest in The Wild (2006), Ozzie the Opossum in Over the Hedge (2006), and General Shanker in Escape from Planet Earth (2012). See more »

Goofs

The movie takes place in Rhode Island as shown by the "Providence Times" newspaper regarding the incident involving Frank vomiting on Mrs. Boyd. However, Frank's car bears a Massachusetts license plate. See more »

Quotes

Leah: Jones, what in the world makes you think I would ever go out with you?
Osmosis: What you talking about? I'm a legend, girl! The chicks line up to divide with me!
Leah: Oh really? 'Cause to me you look like the kind of cell who mostly divides with himself.
Osmosis: Whoa! Who turned off the heat? Somebody pay the bill? It's cold in here.
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Crazy Credits

The Warner Brothers logo comes up looking like a germ-like substance with tentacles (with a blue tint) matching the "feel" of the movie, and is static instead of the modern 3D animated sequence. See more »

Alternate Versions

The DVD release contains three extended (and half-animated) scenes, all of which appear in cut-down form in the final edit:
  • Drix and Jones visit the eyes, while Drix complains that he has to visit the nose and the throat. Jones gets donuts and calls the infodesk on his cell phone while at the eyes.
  • Frank picks his nose during the dam-bursting sequence, and Jones saves Drix from ending up on Frank's fingertip. In the end, they're snorted back up into the sinuses.
  • The race to catch Thrax on his way to the uvula is extended; we see Thrax leap from his car and glide away. Then, after Jones takes the wrong turn, he takes a "shortcut" to the uvula by way of the esophogus, riding a massive acidic Frank-belch up the throat.
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Connections

Referenced in Jeopardy!: Episode #26.26 (2009) See more »

Soundtracks

Turn It Out
Written by Kelvin Mercer, Trugoy The Dove (as David Jolicoeur) and Richard Morninglane
Produced by R. Thentic and De La Soul
Performed by De La Soul featuring Yummy Bingham (as Elizabeth "Yummy" Bingham)
De La Soul appears courtesy of Tommy Boy Music
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User Reviews

 
A Great Class of Hygienic and Human Body Functions
27 November 2003 | by claudio_carvalhoSee all my reviews

Frank (Bill Murray) is a widow without hygienic and bad alimentary habits. He eats food that felt on the floor without cleaning, he does not wash his hands before eating and he eats only junk food. His daughter keeps unsuccessfully trying to correct his behavior. One day, Frank eats a dirty egg and gets a disease. From this moment on, the human body functions are showed through very funny and educational cartoons. The hero, Osmosis Jones, is a white globule, with Chris Rock's voice. The great Farrely brothers again surprise me. This funny (and sometimes scatological movie) is a great class of hygienic and human body functions. Chris Rock and Laurence Fishburne give a great performance with their voices. Bill Murry has the role of a disgusting character. An excellent and very educational movie, indicated also (or specially) for children. My vote is nine.


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Details

Country:

USA

Language:

English

Release Date:

10 August 2001 (USA) See more »

Also Known As:

Osmosis Jones See more »

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Box Office

Budget:

$70,000,000 (estimated)

Opening Weekend USA:

$5,271,248, 12 August 2001

Gross USA:

$13,596,911

Cumulative Worldwide Gross:

$14,026,418
See more on IMDbPro »

Company Credits

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Technical Specs

Runtime:

Sound Mix:

DTS | Dolby Digital | SDDS

Color:

Color (Technicolor)

Aspect Ratio:

2.39 : 1
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