Lewis is a brilliant inventor who meets mysterious stranger named Wilbur Robinson, whisking Lewis away in a time machine and together they team up to track down Bowler Hat Guy in a showdown that ends with an unexpected twist of fate.
Stephen J. Anderson
Frank Detorre is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ...Written by
Anthony Pereyra <firstname.lastname@example.org>
Isaac Hayes were considered for the role of Thrax. See more »
When Osmosis comes back from "The Zit" he greets Leah by saying "Brandy- oh I mean Leah". Brandy Norwood was the voice of Leah. The error was left in because it was acted so well and was funny. See more »
Things are looking grim, as temperatures rise to dangerous levels! We have lost contact with the lower extremities! NNN will stay on the air as long as possible!
In other news, house appliances that can improve your golf swing.
You... you silly twit. Don't you get it? We are going to die!
I knew it, Dan! At the sight of the first dark cloud, you fall apart!
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The title appears as bubbles, which then pop after 5 seconds. See more »
An easter egg on the DVD release shows an energetic montage of action sequences and other shots from the movie. See more »
The Farrelly brothers are dipping into the animation pool. It's colorful and primitive animation. It's pretty good, but that's not really the problem. Surprisingly the problem is Bill Murray and live action stuff.
Frank Detomello is a slob. He eats a hard boiled egg covered with a deadly germ. And we travel inside Frank to see white blood cell policeman Osmosis Jones (Chris Rock) battle evil virus Thrax (Laurence Fishburne) with the help of Drix (David Hyde Pierce).
Bill Murray looks awful as he gets sicker and sicker. I have to ask if we're supposed to laugh at Bill? It's just gross. Not the gross out humor that the Farrellys are known for. It isn't funny at all.
The animated sections are much better. In fact I prefer they cut out the live action stuff. Chris Rock does a good voice. He has good chemistry with David Hyde Pierce's Drix. They need a few more jokes, but I like the City of Frank.
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