Osmosis Jones (2001)

A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.

Directors:

Bobby Farrelly, Peter Farrelly

Writer:

Marc Hyman

Stars:

Laurence Fishburne, Chris Rock, David Hyde Pierce

1 win & 8 nominations.

Cast

Cast overview, first billed only:
Chris Rock	...	Osmosis Jones (voice)
Laurence Fishburne	...	Thrax (voice)
David Hyde Pierce	...	Drix (voice)
Brandy Norwood	...	Leah (voice)
William Shatner	...	Mayor Phlegmming (voice)
Ron Howard	...	Tom Colonic (voice)
Kid Rock	...	Kidney Rock (voice)
Kenny Olson	...	Kidney Rock (voice)
Jason Krause	...	Kidney Rock (voice)
Joe C.	...	Kidney Rock (voice)
Stefanie Eulinberg	...	Kidney Rock (voice)
Jimmie Bones	...	Kidney Rock (voice)
Uncle Kracker	...	Kidney Rock (voice)
Jonathan Adams	...	Additional Character Voice (voice)
Carlos Alazraqui	...	Additional Character Voice (voice)

Storyline

Frank Detorre is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ...

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Plot Keywords:

body | white blood cell | hare krishna | two word title | warner bros. | 

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Taglines:

He's one cell of a guy, and his partner's a real pill

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Genres:

Animation | Action | Adventure | Comedy | Crime | Family | Fantasy | Sci-Fi

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Motion Picture Rating (MPAA)

Rated PG for bodily humor

Details

Official Sites:

Warner Bros. [United States]

Country:

USA

Language:

English

Release Date:

10 August 2001 (USA)

Also Known As:

Osmosis Jones

Filming Locations:

Plymouth, Massachusetts, USA

Box Office

Budget:

$70,000,000 (estimated)

Opening Weekend USA:

$5,271,248, 12 August 2001

Gross USA:

$13,596,911

Cumulative Worldwide Gross:

$14,026,418

Company Credits

Production Co:

Warner Bros., Conundrum Entertainment, Warner Bros. Animation

Technical Specs

Runtime:

95 min

Sound Mix:

DTS Dolby Digital SDDS

Color:

Color (Technicolor)

Aspect Ratio:

2.39 : 1

Did You Know?

Trivia

Jeffrey DeMunn were considered for the role of Bob Detorre.

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Goofs

When Osmosis comes back from "The Zit" he greets Leah by saying "Brandy- oh I mean Leah". Brandy Norwood was the voice of Leah. The error was left in because it was acted so well and was funny.

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Quotes

Scabies: Bruiser, take this punk up to the face and bury him in a blackhead. When we're done, It'll take a Swedish facialist six steaming washcloths to get you out.
Thrax: Hmmm. Sounds like a gas, baby. Bring it on.

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Crazy Credits

The Warner Brothers logo comes up looking like a germ-like substance with tentacles (with a blue tint) matching the "feel" of the movie, and is static instead of the modern 3D animated sequence.

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Alternate Versions

Gonad's Gym logo appears on Drix's suitcase during a scene in police station locker room. In an earlier "cut" of the film, Ozzy and Drix visit an amusement park behind Frank's eye, called "See World".

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Connections

Featured in WatchMojo: Top 10 Biggest Comedy Movie Flops of All Time (2019)

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Soundtracks

My Name Is
Written by Labi Siffre

User Reviews

animation good, but live action gross and boring

The Farrelly brothers are dipping into the animation pool. It's colorful and primitive animation. It's pretty good, but that's not really the problem. Surprisingly the problem is Bill Murray and live action stuff.

Frank Detomello is a slob. He eats a hard boiled egg covered with a deadly germ. And we travel inside Frank to see white blood cell policeman Osmosis Jones (Chris Rock) battle evil virus Thrax (Laurence Fishburne) with the help of Drix (David Hyde Pierce).

Bill Murray looks awful as he gets sicker and sicker. I have to ask if we're supposed to laugh at Bill? It's just gross. Not the gross out humor that the Farrellys are known for. It isn't funny at all.

The animated sections are much better. In fact I prefer they cut out the live action stuff. Chris Rock does a good voice. He has good chemistry with David Hyde Pierce's Drix. They need a few more jokes, but I like the City of Frank.