What do animals, allergies and a bet have in common? A commitment-phobic woman named Lisa Harris. Lisa may hold the record for most failed short-term relationships in modern history. It's not that she doesn't want to find her true love, it's just that she doesn't seem to know what true love means. It's with the idea of helping Lisa that her mom, Gwen bets her she won't be able to stay with her current boyfriend, Simon through Thanksgiving, a record three weeks away. From the moment Lisa accepts the challenge, her life changes. No sooner has Lisa made the bet than Simon is unexpectedly called away on business. Determined not to lose, Lisa lets her roommate Amy talk her into substituting another man for Simon a handsome carpenter named Mike. But life's not so simple... not only does Lisa have to contend with Mike's allergy to her pet rabbit but with the unexpected return of Mike's beautiful but manipulative ex-girlfriend George. While George poses a threat, it soon becomes clear to Lisa...