A genetically engineered mouse (who sounds like Orson Welles) and his insane cohort make nightly attempts to take over the world.
Did You Know?
A bootleg tape of a short-tempered (and foul-mouthed) Orson Welles
arguing with a recording engineer during a voice-over session has been widely distributed. It was used as the basis for an episode of this show, with The Brain reading cleaned-up versions of Welles' rantings. The episode's title, "Yes, Always", is taken from one of Orson's complaints. See more
Yes, finally! The Happy Sappy Children of Many Lands ride! Where cheering music will spread the message that a mouse should rule the world!
Oh no, Brain. Narf! You're thinking of that other park in Orlando.
Towards the end of the credits you'll find the definition for one of the polysyllabic words used by Brain in that week's episode. See more
The 'Nickelodeon Network' adds the 'Nickelodeon' logo into the opening credits on various objects. See more
Pinky and the Brain Theme - Original Version See more