This is a sketch-comedy show. The twist here is that all of the sketches (even the monologue) are connected in some strange way.
The first late-night comedy show with an attention span shorter than yours.
Did You Know?
Even though Bob and David joke about getting hate mail a lot in Mr. Show, the only time they actually received some was from a military veteran offended by a sketch where a character attempts to deficate on an American flag. Bob and David then called up the veteran and realized he hadn't watched the entire sketch, because the character never successfully managed to deficate on the flag. See more
Towards the end of one episode in the fourth season, the show offers the math problem "If he drives 15 MPH for fifteen minutes, how far has he travelled? Answer at the end of the show." When the end credits roll, they say that the answer is 3.5 The correct answer is 3.75 See more
Sad songs are nature's onions.
At the end of each episode's credits under "Special Thanks," there is at least one random name that had nothing to do with the show. This is pointed out by David Cross in the DVD commentary for the first episode. See more
Referenced in Defective Man!