A small Indian man on a creaky cart with powers of illusion is believed to have the ability to take over people's bodies and kill them by leaping into their anal cavity. Doggett and Scully try to stop his gruesome killing spree.
Three months after Mulder's funeral, another alien abductee's body comes back to life. Skinner exhumes Mulder hoping that he too can be revived. Skinner faces an impossible decision when Krycek offers him a vaccine that can save Mulder.
Mulder requests reassignment to the X-Files but is denied by Kersh. When a man with information about an alien invasion is killed on the White House lawn, Mulder conducts his own investigation to find further evidence of colonization.
Doggett attempts to uncover the truth about a woman with superhuman abilities who is somehow connected to scientific experiments being conducted in a lab aboard a secret ship that stays at sea year round.
A professor/inmate in a psychiatric ward may be influencing other men to kill ritualistically. Though Doggett sees it as pure manipulation, Reyes can't help but suspect none else but the devil himself possessing the professor's body.
Agent Dogget has been shot and hospitalized. The only suspect is his partner. However, she was 14 miles away when the shooting occurred. The team sticks together to solve the case of being in two places at one time.