Harris, who is not a Republican like McCain, played a presidential candidate in 1992's movie "Running Mates". Producers of "Game Change" have not yet revealed who will play Barack Obama, Hillary Clinton and Joe Biden, three other principals in the 2008 campaign.
The telefilm is based on the bestselling book of the same name by John Heilemann and Mark Halperin. Jay Roach and Danny Strong who collaborated on HBO's Emmy-winning "Recount" have teamed up once again as director and scriptwriter respectively.
Shooting begins this Spring in Maryland. "This is good subject matter [politics] to be shooting in Maryland, in and around Baltimore.