The Cuban actress came to prominence last year with her performance as holographic companion Joi in 'Blade Runner 2049,' opposite Ryan Gosling.
In 'Waiting for Helen,' she will play a waitress who may be an innocent patsy or a sadistic sociopath.
According to the official synopsis: "A detective tells a stranger the story of an attractive, young waitress named Helen, who befriended a customer and was asked to help prove her husband's infidelity. People end up dead."
The detective must then prove Helen is either innocent or guilty before the night is over, or her life will be.
Projects in the pipeline for de Armas include crime drama 'Three Seconds,' alongside Rosamund Pike; Danny Boyle's musical comedy based on the music of The Beatles; and 'The Night Clerk,' about a voyeuristic hotel clerk who becomes the subject of a murder investigation, which also stars Tye Sheridan and Helen Hunt.
Pollak, best known for his roles in 'The Usual Suspects,' 'A Few Good Men,' and 'The Whole Nine Yards,' will also star in the movie.