Exteriors of 'Doris Mann''s house were shot at home of actress Connie Stevens. Connie Stevens, like Carrie Fisher's mother Debbie Reynolds, was once married to Carrie Fisher's father Eddie Fisher. Stevens is the mother of Carrie Fisher's half sisters Tricia Leigh Fisher and Joely Fisher.
In 2016, Vulture reported that in Debbie Reynolds's autobiography, she said that when she asked Mike Nichols for the role of Doris Mann (which was based by Reynolds's daughter, Carrie Fisher, on Reynolds herself), Nichols said she wasn't right for the part.
Although Meryl Streep did her own singing for this movie, she did not repeat her performance of Shel Silverstein's Oscar-nominated song "I'm Checkin' Out" at the Academy Awards ceremony because she was very close to giving birth to her fourth child. Country star Reba McEntire performed the song at the ceremony instead, despite the fact that eight of her friends and band members had died in a plane crash just a week and a half earlier. "I'm Checkin' Out" did not win Best Song that year; the song that won instead was "Sooner or Later" from Dick Tracy, which had music and lyrics by Stephen Sondheim. Sondheim had also created specially tailored lyrics for his Follies song "I'm Still Here" specifically to be sung by Shirley MacLaine in Postcards from the Edge.
In a scene from early in the movie, Lowell is dressing down Suzanne for her drug-use on set, and the film crew are clearly seen near-by. One of the crew is wearing a crew shirt from "Evil Angels," the Australian title of A Cry in the Dark, which starred Meryl Streep.
The band accompanying Meryl Streep at the end of the film is Blue Rodeo, one of the most popular and respected rock groups in Canada, who were virtually unknown in the US at the time of the film's release. After hearing their music being played in a limo, by the driver, Streep wanted them to contribute to the soundtrack.